For small breeds, the optimal mating age is 5 months for does and 6 for buck. For medium breeds, it is 6 for does and 7 for bucks. And for large breeds, it is 8 for does and 9 for bucks.
In commercial setting, males and females are housed together, but the males are neutered, not the females. To house the rabbits, you don't need acres of land. I think 1m2 per rabbit is more than enough for rabbits meant for slaughter. But as for breeders, they are normally housed individually so...